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Viagra tablets active ingredient: Sildenafil citrate by pfizer Viagra informationThis drug is taken by mouth as needed between four hours and one-half hour before sexual activity (about one hour before is most effective). Take only as directed, usually once daily as needed. Sildenafil works along with sexual stimulation to help achieve an erection. [more info] Viagra (made by Pfizer) is used for the treatment of male impotency. The active ingredient in Viagra is a specific inhibitor of phosphodiesterase 5. Phosphodiesterase 5 (PDE5) cleaves the ring form of cyclic GMP (cGMP) a cellular second messenger similar to cAMP. The inhibition of the phosphodiesterase allows for the persistence of cGMP which promotes the effects of cGMP production. In this case, it allows for increased blood flow into the penis which may result in an erection. |
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